Dexamethasone and Block Duration in Upper Extremity

Not Applicable

Terminated

• Conditions: Duration of Pain Relief
• Interventions: Drug: Dexamthsone; Drug: Bupivacaine

• Registration Number: NCT01756573
• Lead Sponsor: University of Chicago

Brief Summary

Effect of dexamethasone on prolonging upper extremity block is well known. But it not known if the effect comes from its local effect on the nerves or from its general analgesic effect. In this study we will compare the systemic effect to its local effect to find out if there is a difference or not.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2012-12-20
• Study First Submitted QC: 2012-12-20
• Study First Posted: 2012-12-27
• Study Start: 2013-01
• Primary Completion: 2015-01
• Study Completion: 2015-01
• Results First Submitted: 2016-06-16
• Status Verified: 2019-04
• Results First Submitted QC: 2019-04-22
• Last Update Submitted: 2019-04-22
• Results First Posted: 2019-05-14
• Last Update Posted: 2019-05-14

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 5

Inclusion Criteria

• age 18-75, no contraindication to regional anesthesia,

Exclusion Criteria

• opioid user, chronic pain conditions, peripheral neuropathy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Bupivacaine with Dexamethasone	Dexamthsone	Dexamethasone will be mixed with bupivacaine
Intravenous Dexamethasone	Dexamthsone	Dexamethasone will be given intravenously
Bupivacaine	Bupivacaine	Control
Bupivacaine with Dexamethasone	Bupivacaine	Dexamethasone will be mixed with bupivacaine
Intravenous Dexamethasone	Bupivacaine	Dexamethasone will be given intravenously

Primary Outcome Measures

Name	Time	Method
Analgesia Duration	72 hrs

Trial Locations

Locations (1)

University of Chicago Medical Center; 🇺🇸 Chicago, Illinois, United States