Comparison of local numbing drug (lidocaine) when given directly into blood or as a throat spray to decrease the response to passing an artificial breathing tube through the throat in patients with elevated BP posted for surgery
Not Applicable
- Conditions
- Health Condition 1: I10- Essential (primary) hypertension
- Registration Number
- CTRI/2022/05/042595
- Lead Sponsor
- il
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Adult patients between 18 â?? 80 years belonging
to American Society of Anesthesiologists grade II
with controlled hypertension ( Preoperative blood
pressure less than 140/90 mm of Hg, controlled
using single or combination of antihypertensive
drugs)undergoing oro-tracheal intubation. posted
for elective non cardiac surgery lasting more than
one hour.
Exclusion Criteria
1. Patients with anticipated difficult airway
2. Patients who are allergic to lignocaine
3. Patients with history of ischemic heart
disease and any vascular aneurysm
4. Pregnant women
5. Patients with active Gastroesophageal
reflux disease GERD
6. Patients with oropharyngeal pathology
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the difference between the <br/ ><br>preinduction and one minute post intubation <br/ ><br>systolic arterial pressure, between the atomized <br/ ><br>topical lidocaine group and intravenous lidocaine <br/ ><br>group following laryngoscopy and tracheal <br/ ><br>intubation. <br/ ><br>Timepoint: pre intubation and one minute post intubation
- Secondary Outcome Measures
Name Time Method 1.Mean arterial pressure <br/ ><br>2.Diastolic pressure <br/ ><br>3.Heart rate <br/ ><br>4.Rate Pressure Product <br/ ><br>5.ECG changes <br/ ><br>6.Arrhythmias <br/ ><br>Timepoint: One minute intervals upto 10 minutes post intubation