Genetics of pelvic organ prolapse; identification of specific gene defects in patients and their family members.
Recruiting
- Conditions
- Pelvic organ prolapseUrogenital prolapse1003860810046828
- Registration Number
- NL-OMON33518
- Lead Sponsor
- niversitair Medisch Centrum Sint Radboud
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
First and second degree relatives of patients with COL3A1 2209G>A polymorphism
Exclusion Criteria
-Genetic diseases with a known increased risk of POP (such as Ehlers Danlos, Marfan and Steinert*s disease)
-Problems with regards to the patient*s understanding of the study
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Presence of the COL3A1 2209G>A polymorphism in family members of patients with<br /><br>the homozygous form of this polymorphism. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Presence of pelvic organ prolapse and related conditions such as inguinal<br /><br>hernia in family members of patients with the homozygous form of the COL3A1<br /><br>2209G>A polymorphism.</p><br>