Stepwise treatment of uncontrolled high blood pressure in general practice
- Conditions
- TherapyresistantUncontrolledHypertensionPrimary Care TherapieresistentOngecontrolleerdHypertensie Eerste lijn
- Registration Number
- NL-OMON22505
- Lead Sponsor
- MC Utrecht
- Brief Summary
one
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 240
Patients aged > 18 years and < 80 years with an office blood pressure > 140/90 mmHg, on at least two blood pressure measurements per visit and on at least two occasions in the last year despite prescription of three or more blood pressure lowering drugs of different classes at adequate dosage, with for each antihypertensive drug at least 1 prescription of 3 months. During the inclusion consultation, the office blood pressure should be > 140/90 mmHg (measured according to the NHG CVRM guideline).
- A short life expectancy (< 6 months) as judged by the GP. - Inability to understand or conform to the stepwise protocol. - Unwillingness to provide a written informed consent. - In case of suspicion of a hypertensive crisis (systolic blood pressure ≥ 200 mmHg and/or diastolic blood pressure ≥ 120 mmHg) the patient is referred for further evaluation. If a hypertensive crisis is excluded, the patient can be included in the study. - Atrial fibrillation (because of difficulties to interpret 24 hour BP measurements) - Pregnancy or breast feeding. - Severe co-morbidity, which seriously interferes with diagnostic procedures or possible treatment.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method