A clinical trial to study the effect of Ketamine spray versus Dexmedetomidine spray at surgical site during closure in lumbar spine fixation surgery for postoperative pain relief
Phase 1
- Conditions
- Health Condition 1: O- Medical and Surgical
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Lumbar spine patients posted for spine instrumentation surgery.
2. Age group between 18 and 60 years.
Exclusion Criteria
1. Refused to participate in the study.
2. A body mass index exceeding 30 kg/m2
3. Allergy to any studied medication
4. Hepatic or Renal insufficiency
5. Multiple level spine surgery or simultaneous/recent surgery
6. Antihypertensive medication with clonidine or other a2 agonists.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Duration of postoperative analgesia (VAS)Timepoint: 30mins,hours: 1,2,4,6,24
- Secondary Outcome Measures
Name Time Method Total rescue analgesic requirement in 24hr. <br/ ><br>Any associated side effects like nausea /vomiting/sedation/shivering etc.Timepoint: 24 hours