Can taking probiotics ('friendly bacteria') encourage weight loss in people who are overweight?

Not Applicable

Completed

• Conditions: Healthy overweight individuals aged 45 and over following normal lifestyle; Not Applicable

• Registration Number: ISRCTN18030882
• Lead Sponsor: Cultech Ltd

Brief Summary

2021 results in https://pubmed.ncbi.nlm.nih.gov/33408364/ (added 12/01/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-11-27
• Study Completion: 2020-02-17
• Last Update Posted: 25 January 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

1. Male or female, aged between 45 to 65 years at start of study
2. Waist circumference >89 cm (women) or >100 cm (men) at start of study
3. Body mass index (BMI) between 25 and 29.9 at start of study
4. Willing to provide fasting blood samples at days 0, 180 and 270

Exclusion Criteria

1. Immunodeficiency/ immunosuppressive therapy on-going
2. Diagnosed diabetes
3. Pregnant or planning pregnancy
4. Anamnesis of ischemic heart disease, heart failure, prolonged QTc interval, rhythm and conduction disorders – absolute arrhythmia, ventricular extrasystole, atrioventricular block or any other cardiovascular disease deemed by the investigator as a risk for the participation in the study
5. Severe systemic disease (cancer, dementia, advanced organ failure)
6. Weight loss in the last 3 months prior to start of study, which cannot be explained with a dietary regimen or increased physical activity
7. Not on statin therapy nor received any statin therapy in the last 6 months prior to start of study

Study & Design

• Study Type: Interventional
• Study Design: Not specified