Effects of probiotics supplementation on risk factors for cardiovascular disease in obese hypertensive individuals

Not Applicable

Recruiting

• Conditions: Essential (primary) hypertension. Insulin resistance. Hyperlipidemias. Obesity.; C18.452.394.968.500; C18.452.584.500.500; C18.654.726.500

• Registration Number: RBR-7jw4ry
• Lead Sponsor: niversidade do Estado do Rio de Janeiro

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-01-14
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Individuals aged 40 to 65 years. Both sexes, women in post-menopausal period. Body mass index equal or more than 30.0 and less than 40.0 kg per m². Diagnosis of hypertension on regular treatment with antihypertensive drugs for at least 4 weeks. Signature of the informed consent.

Exclusion Criteria

Individuals with evidence of secondary hypertension or presenting blood pressure equal or greater than 160 x 100 mmHg. Diabetes mellitus and or use of insulin or oral hypoglycemic agents. Diagnosis of malignant or autoimmune diseases. Chronic kidney or hepatic diseases. Clinical signs of heart failure or of changes in thyroid function. Use of probiotics, prebiotics, symbiotics, antibiotics, hypolipidemic drugs, hormone replacement therapy, proton pump inhibitors, antioxidant and/or anti-inflammatory supplements including vitamin, mineral or omega 3 in the last 3 months. Recent changes (last 3 months) in body weight (equal or greater than 3kg) and/or in food intake. Current or former smokers (last 12 months). Physical activity practitioners. Vegetarians. Pregnant or lactating women.

Study & Design

• Study Type: Intervention
• Study Design: Not specified