Immune effects of acidic and neutral oligosaccharides in the nutrition of preterm infants: CARROT study.
- Conditions
- Prebiotics, Immune effects, Gastrointestinal tract, preterm infantsPrebiotica, Immuunsysteem, Maagdarmkanaal, Tevroeggeboren kinderen
- Registration Number
- NL-OMON27978
- Lead Sponsor
- Ruurd M. van Elburg / Gunther Boehm
- Brief Summary
Westerbeek EAM, van den Berg A, Lafeber HN, Knol J, Fetter WPF, van Elburg RM. The intestinal bacterial colonisation in preterm infants: A review of the literature. Clin Nutr. 2006;25:361-368. van den Berg A, van Elburg RM, Westerbeek EAM, Twisk JWR, Fetter WPF. Glutamine-enriched enteral nutrition in very-low-birth-weight infants and effects on feeding tolerance and infectious morbidity: a randomized controlled trial. Am J Clin Nutr 2005;81:1397-1404. Fanaro S, Jelinek J, Stahl B, Boehm G, Kock R, Vigi V. Acidic oligosaccharides from pectin hydrolysate as new component for infant formulae: Effect on intestinal flora stool characteristics, and pH. J Pediatr Gastroenterol Nutr. 2005;41:186-190.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 108
Infants born with a gestational age of less than 32 weeks and/ or a birthweight of less than 1500 gram
1. Severe congenital disorders, like cardiac disorders, syndromal disorders, immunodeficiency disorders;
2. Congenital disorders of the gastrointestinal tract.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method