Muscarinic receptor genotype

• Conditions: benign prostatic hypertrophia; overactive bladder; 10017977; 10004994; 10006436

• Registration Number: NL-OMON30915
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 200

Inclusion Criteria

Male patients treated in the department of Urology of the Amsterdam Medical Center (AMC) of any age. Any patient that receives any kind of treatment in which prostate tissue is harvested and and not required for pathological analysis.

Exclusion Criteria

none

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Main study parameters/endpoints: Genotype for the polymorphism in the M2<br /><br>receptor gene promoter will be related to abundance of M2 receptor mRNA in<br /><br>prostatic tissue; mRNA for housekeeping genes and for other muscarinic receptor<br /><br>subtypes will be internal controls </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable</p><br>