Oxygen Preconditioning Prevents Contrast-Induced Nephropathy after contrast-enhanced Computed Tomography
- Conditions
- Contrast-Induced Nephropathy
- Registration Number
- JPRN-UMIN000016411
- Lead Sponsor
- ational Hospital Organization Yokohama Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 1100
Not provided
1)Patients within 2 weeks after the acute coronary syndromes (acute myocardial infarction, unstable angina) 2)Patients presenting shock (systolic blood pressure <90 mmHg) 3)Patients with a history of a severe contrast medium allergy 4)Patients with chronic kidney disease which eGFR less than 30 mL/min/1.73m2 5)Patients were administrated the contrast medium within 10 days 6) Patients with oxygen saturation of peripheral artery:SpO2 less than 90% recorded 7)Patients with chronic obstructive pulmonary disease or patients with risks for CO2 narcosis (including history of CO2 narcosis) 8)Patients receiving home oxygen therapy 9)Patients undergoing hemodialysis or peritoneal dialysis 10)Patients who have taken biguanides within 48 hours 11) Patients with severe infections, patients in the perioperative period, or those with serious injury, poor nutritional status, in a starvation state, or state of debility 12)Patients that are scheduled operation within two weeks 13) Patients with confirmed or suspected rhabdomyolysis 14) Patients with confirmed or suspected pituitary or adrenal insufficiency 15) Patients with paraquat poisoning 16)Patients who are pregnant or may be pregnant 17)Patients with piece renal,renal hypoplasia,or nephrectomy (including partial nephrectomy) 18)Patients administrated oxygen 24 hours before the contrast enhanced computed tomography 19)Patients for whom planing the treatment by intravenous drip infusion or oral rehydration therapy 20)Patients will be undergoing emergency computed tomography 21)Patients can not have a oral rehydration therapy 22)Patients whose doctors judged them as unsuited to participate in this clinical study 23)Patients during the follow-up period of this clinical study or with the history of participation to this clinical study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of CIN within 72 hours after the contrast enhanced computed tomography
- Secondary Outcome Measures
Name Time Method