Effect of the Transmuscular Quadratus Lumborum Block on Duration of Stay in Recovery

• Conditions: Anesthesia, Local
• Interventions: Drug: Ropivacaine injection

• Registration Number: NCT04951752
• Lead Sponsor: Zealand University Hospital

Brief Summary

The study will review data collected in 5 previously completed randomised controlled trials with a new primary outcome: to assess whether administration of the transmuscular quadratus lumborum block has an impact on the time an individual patient stays in the postanaesthesia care unit and how much opioid is consumed during this specified time.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-04-14
• Study First Submitted: 2021-04-14
• Status Verified: 2021-06
• Study First Submitted QC: 2021-06-29
• Last Update Submitted: 2021-06-29
• Study First Posted: 2021-07-07
• Last Update Posted: 2021-07-07
• Primary Completion: 2021-08-01
• Study Completion: 2021-08-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 307

Inclusion Criteria

• Elective Surgery

Exclusion Criteria

• Inability to cooperate
• Allergy to local anaesthetics or opioids
• Inability to understand Danish
• Regular intake of opioids
• Local infection at site of injection

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Hemicolectomy, Active treatment	Ropivacaine injection	2x30mL 0.375% Ropivacaine administered by way of transmuscular quadratus lumborum block
Percutaneous nephrolithotomy, Active treatment	Ropivacaine injection	1x30mL 0.75% Ropivacaine administered by way of transmuscular quadratus lumborum block
Elective Caesarean section, Active treatment	Ropivacaine injection	2x30mL 0.375% Ropivacaine administered by way of transmuscular quadratus lumborum block
Nephrectomy, Active treatment	Ropivacaine injection	2x30mL 0.375% Ropivacaine administered by way of transmuscular quadratus lumborum block
Hysterectomy, Active treatment	Ropivacaine injection	2x30mL 0.375% Ropivacaine administered by way of transmuscular quadratus lumborum block

Primary Outcome Measures

Name	Time	Method
Duration of recovery	0-300 minutes	Minutes from arrival in PACU to completed recovery (arrival until ready for departure)

Secondary Outcome Measures

Name	Time	Method
Total time spent in recovery	0-300 minutes	Minutes from arrival in PACU to actual departure time (arrival until actual departure)
Duration of stay at PACU after completed recovery	0-300 minutes	Minutes from completed recovery to actual departure from PACU
Total opioid consumption in PACU	0-300 minutes	Total amount of opioid administered, converted to Oral Morphine Equivalents
Highest pain score in PACU	0-300 minutes	Highest reported Numeric Rating Scale of pain during stay in recovery

Trial Locations

Locations (1)

Zealand University Hospital; 🇩🇰 Roskilde, Denmark