Postoperative analgesia for total knee replacement: a comparison between intrathecal morphine and peripheral nerve blocks
Not Applicable
Completed
- Conditions
- Analgesia following total knee replacementsSurgeryAnalgesia
- Registration Number
- ISRCTN53794597
- Lead Sponsor
- Gwent Healthcare NHS Trust (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
1. Primary elective total knee replacement
2. Fit patients of American Society of Anesthesiologists (ASA) classification one to three
Exclusion Criteria
1. Patients who refuse consent
2. Revision surgery
3. Had adverse reaction or a contraindication to the administration of morphine, local anaesthetics, non-steroidal anti-inflammatory drugs, paracetamol, tramadol, centrineuraxial block and peripheral nerve blocks
4. Patient with history of chronic pain other than at the site of joint replacement
5. Used regular strong opioids
6. Renal impairment
7. Liver impairment
8. ASA physical status greater than three
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Quality of pain relief on movement of knee joint.
- Secondary Outcome Measures
Name Time Method The secondary outcome measures include: <br>1. The number of patients requiring rescue analgesia<br>2. Time for the first dose of Tramadol<br>3. The incidence of the adverse effects of Morphine and Visual Analogue Scale (VAS) for patient satisfaction at 48 hours