Comparison of a drug in two different routes for ultrasound guided erector spinae block in adult females undergoing modified radical mastectomy surgery for breast cancer

Not Applicable

Not yet recruiting

Conditions: Administration,

Registration Number: CTRI/2020/03/023881

Lead Sponsor: Vardhman Mahavir Medical College and Safdarjung Hospital

Brief Summary: This study is designed to compare the clinical efficacy of perineural dexamethasone added as an adjuvant to 0.5% ropivacaine in ultrasound guided erector spinae blocks with intravenous dexamethasone administered along with 0.5% ropivacaine in ultrasound guided erector spinae block for adult females undergoing modified radical mastectomy.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: Female

Target Recruitment: 75

Inclusion Criteria

This study will be conducted on adult females of age 18-65 years of American Society of Anaesthesiologists(ASA) physical status I or II,weighing 40-85 kgs scheduled for elective MRM surgery under general anaesthesia.

Exclusion Criteria

1.Contraindications to blocks (like patients with coagulopathy or taking anticoagulants and local infection at the site of needle insertion) or recent neurological deficit.
2.Patients with history of hypersensitivity or allergy to drugs used in the study.
3.Patients suffering from cardiac,renal,hepatic and respiratory insufficiency.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the duration of analgesia using perineural dexamethasone added as an adjuvant to 0.5% ropivacaine in ultrasound guided erector spinae blocks with intravenous dexamethasone administered along with 0.5% ropivacaine in ultrasound guided erector spinae block for adult females undergoing modified radical mastectomy	72 hours postoperative period

Secondary Outcome Measures

Name	Time	Method
To compare the duration of sensory block by administration of perineural dexamethasone added as an adjuvant to 0.5% ropivacaine in ultrasound guided erector spinae blocks with intravenous dexamethasone administered along with 0.5% ropivacaine in ultrasound guided erector spinae block for adult females undergoing modified radical mastectomy	72 hours postoperative period
To compare the quality of pain control by administration of perineural dexamethasone added as an adjuvant to 0.5% ropivacaine in ultrasound guided erector spinae blocks with intravenous dexamethasone administered along with 0.5% ropivacaine in ultrasound guided erector spinae block for adult females undergoing modified radical mastectomy using Numerical Rating Scale(NRS)	72 hours postoperative period

Trial Locations

Locations (1): Vardhman Mahavir Medical College
🇮🇳
Delhi, DELHI, India
Vardhman Mahavir Medical College
🇮🇳Delhi, DELHI, India
Gokila D
Principal investigator
9791375305
gokila.devarajan151293@gmail.com