NCT04580186Unknown不适用
Outcome Of Classic Bladder Exstrophy Repair, Assiut University Experience
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 10
- 主要终点
- Evaluate results of the technique used for bladder exstrophy repair
研究概览
简要总结
- To review surgical and medical outcomes of the previous repaired bladder exstrophy cases.
- To present recent developments in surgical techniques and care of these patients.
详细描述
- Exstrophy-epispadias complex (EEC) is a spectrum of genitourinary malformations resulting from abnormal cloacal development .
- CBE, the most common form with an incidence of 2.68 in 100,000 live births is characterized by an evaginated bladder plate, epispadias and an anterior defect of the pelvis, pelvic floor and abdominal wall
- The single most important predictor of long-term bladder growth and continence is successful primary bladder closure .
- The staged reconstruction of bladder exstrophy was proposed by Jeff and led to significant improvements in continence and renal function with excellent cosmetic results.
- The initial staged management consisted of newborn bladder and posterior urethral closure followed by bladder neck reconstruction at 2 to 3 years of age and later epispadias repair.
- The understanding that appropriately timed epispadias repair may lead to enhancement in bladder capacity led to performance of epispadias repair at 2 to 3 years of age followed by later bladder neck reconstruction. The current modification of the staged repair consists of secure bladder and posterior urethral closure in infancy followed by epispadias repair at 6 to 12 months of age and bladder neck reconstruction when the patient is able to cooperate in a good voiding program.
- Complete repair surgery is performed in a single procedure that closes the bladder and the abdomen and repairs the urethra and outer sex organs
- A failed classic bladder exstrophy (CBE) closure is defined by wound dehiscence, bladder prolapse, bladder outlet obstruction, or formation of a vesicocutaneous fistula.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All patient with CBE who underwent repair at Assiut university hospital.
排除标准
- •Cloacal exstrophy isolated epispadias previous failed repair out Assiut university hospital
结局指标
主要结局
Evaluate results of the technique used for bladder exstrophy repair
时间窗: base line
complete bladder exstrophy repair
次要结局
- Present recent development in care and repair of these patients(baseline)
研究者
Mohamed Emad Eldin Anwar
assistant lecturer
Assiut University
相似试验
Unknown
不适用
Kidney Function in Patients With Bladder ExstrophyClassic Bladder ExstrophyRenal FunctionGFRProteinuriaNCT02192801Tel-Aviv Sourasky Medical Center30
尚未招募
不适用
Pelvic Osteotomy in Bladder ExstrophyBladder ExstrophyNCT06717386Sohag University10
终止
不适用
Early Versus Late Voiding Trials After Prolapse RepairUrinary RetentionPelvic Organ ProlapseNCT02739256University of Pittsburgh57
已完成
不适用
Long-term Outcomes of Patients Treated for Bladder Exstrophy by Questionnaires.Bladder ExstrophyNCT05690594Hospices Civils de Lyon42
已完成
不适用
BO and DO in Women With Cystocele Before and After Cystocele RepairBladder OversensitivityDetrusor, OveractiveNCT04981054National Taiwan University Hospital483