Kidney Function in Patients With Bladder Exstrophy

• Conditions: Renal Function; GFR; Classic Bladder Exstrophy; Proteinuria

• Registration Number: NCT02192801
• Lead Sponsor: Tel-Aviv Sourasky Medical Center

Brief Summary

Patients with classical bladder exstrophy undergo many surgical interventions with secondary urinary tract infections complicating their course. lately primary definitive surgical correction of this congenital anomaly has been implemented with satisfactory results. Although bladder exstrophy patients are born with normal kidneys, infectious and mechanical surgical complications can potentially damage their kidneys in the long-term. therefore we decided to evaluate renal function in the long-term in these patients.

Detailed Description

Not available

Study Timeline

• Status Verified: 2014-01
• Study First Submitted: 2014-01-30
• Study Start: 2014-04
• Study First Submitted QC: 2014-07-16
• Last Update Submitted: 2014-07-16
• Study First Posted: 2014-07-17
• Last Update Posted: 2014-07-17
• Primary Completion: 2016-04

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• All patients with classic bladder exstrophy treated and followed in Pediatric urology clinic in Dana Children Hospital and Outpatient Clinic

Exclusion Criteria

• No

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Renal function	1 day (last visit )	Creatinine and GFR estimation , proteinuria, albuminuria will be assessed as measures of renal function as well as renal mass estimation through renal size as by ultrasound and in certain cases through dimercaptosucicnic acid (DMSA)renal scan

Trial Locations

Locations (1)

Pediatric Outpatient Clinic Dana Children Hospital Tel Aviv Sourasky medical center; 🇮🇱 Tel Aviv, Israel