Influence of Intramuscular Temperature on the Textural Characteristics of the B-mode Ultrasound Image.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Muscle echointensity (0-255 a.u.).
研究概览
简要总结
Echointensity and echotexture have been used as a physiological marker for changes in skeletal muscle quality and structure caused by physical training, low activity, ageing and some neuromuscular disorders. However, there are some influencing factors on muscle echo-intensity and echotexture, such as temperature, which may not be taken into account when performing an ultrasound assessment and may alter the results.
This study aims to investigate the effects of muscle temperature on echointensity and other 2nd order echotextures variables such as homogeneity, contrast, correlation and entropy of muscle tissue, in order to gain a better understanding of this correlation and minimise its influence, which would allow greater precision in the use of muscle ultrasound as a diagnostic tool.
The methodology of this study includes firstly the acquisition of ultrasound images of the vastus lateralis muscle. This acquisition will be performed during the continuous recording of muscle temperature, carried out during a passive cooling process after 20 min of heating using microwave equipment. In addition, to standardise the results, a correction factor will be calculated to compensate for the influence of subcutaneous adipose tissue thickness on echogenicity and echotexture.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Acceptance of participation in the study.
- •Healthy subjects.
- •Subjects between the ages of 18 and 65.
排除标准
- •Have known neurological, cardiovascular, metabolic or orthopedic conditions that prevent them from participating in the study.
- •Present metal implants in the heating area.
- •Wear a pacemaker.
- •Perform physical activity during the 48 hours prior to data collection.
- •Contraindications of dry needling such as: Belonephobia, history of abnormal reaction to the puncture or injection, anticoagulant treatment or thrombocytopenia, lymphedema over the area of intervention, severely compromised immune system, vascular diseases, diabetes mellitus, pregnancy, epilepsy, allergy to metals or that the intervention area has wounds, scars, tattoos, or stains.
结局指标
主要结局
Muscle echointensity (0-255 a.u.).
时间窗: During intervention
Muscle echointensity is calculated by the mean gray level value of the muscle Range of Interest (ROI). (0-255 a.u.)
Muscle echovariance (0-255 a.u.).
时间窗: During intervention
The echovariance is determined by the relationship between the standard deviation and the average pixel intensity obtained from the histogram of the muscle ROI. (0-255 a.u.)
Muscle homogeneity.
时间窗: During intervention
It is a second-order parameter (GLCM) that measures the uniformity of the muscle ROI composition.
Echointensity correction factor for adipose thickness
时间窗: Pre-intervention
The measurement of subcutaneous adipose thickness will be carried out through the average of the distance from the skin to the aponeurosis coinciding with the superficial interface of the muscle and with different pressures of the probe on the skin. This measure will be used to develop a correction factor that allows compensating the influence of this variable on echogenicity and echotexture, standardizing the results.
Muscle energy or second angular momentum.
时间窗: During intervention
It is a second order parameter (GLCM) that measures textural uniformity of the muscle ROI
Contrast.
时间窗: During intervention
It is a second-order parameter (GLCM) that measures local variations in gray levels of the muscle ROI.
Textural Correlation.
时间窗: During intervention
It is a second-order parameter (GLCM) that expresses linear gray-level dependencies of the muscle ROI.
Entropy.
时间窗: During intervention
It is a second-order parameter (GLCM) to measure muscle ROI disorder.
Muscle temperature (ºC).
时间窗: Pre-intervention and during intervention
Measurement of intramuscular temperature of the right vastus lateralis of the quadriceps (ºC)
次要结局
- Age (years)(Pre-intervention)
- Sex (female or male)(Pre-intervention)
- Dominance(Pre-intervention)
- Body mass index(Pre-intervention)
研究者
SERGIO MONTERO NAVARRO
Principal Investigator
Cardenal Herrera University