Endodontic Microsurgery With the Use of L-PRF Block: a Randomized Controlled Clinical Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Apical Periodontitis
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Amount of peri-apical bone healing
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
This study evaluates the effect of leucocyte and platelet rich fibrin Block (L-PRF Block) during endodontic microsurgery (EMS) on patient's post-operative comfort and periapical bone healing in large peri-apical lesions.
Detailed Description
This study evaluates the effect of leucocyte and platelet rich fibrin Block (L-PRF Block) during endodontic microsurgery (EMS) on patient's post-operative comfort and periapical bone healing in large peri-apical lesions. The trial design is an open randomized controlled clinical trial with two groups. Half of the participants will receive EMS with L-PRF Block (experimental group), the other half without (control group).
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Amount of peri-apical bone healing
Time Frame: 1 year
Amount of periapical bone healing in time: measured with Cone Beam Computed Tomography (CBCT).
Secondary Outcomes
- Patient related outcomes(7 days)
- Bone or scar tissue healing(1 year)
- Success & survival rate(1 year)
- Dentinal defects(1 year)