A study to find out how well pregabalin and gabapentin when given before surgery provides pain relief after surgery for lower abdominal surgeries done using spinal anaesthesia.
Not Applicable
- Conditions
- Health Condition 1: K35-K38- Diseases of appendixHealth Condition 2: K40-K46- HerniaHealth Condition 3: N80-N98- Noninflammatory disorders of female genital tract
- Registration Number
- CTRI/2019/03/018053
- Lead Sponsor
- Dr Pavithra
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients of both sexes consenting for lower abdominal surgeries under subarachnoid block
BMI between18-25 kg/m2
Exclusion Criteria
ASA III and above physical status
Pregnancy and Lactating mother
Known psychiatric disorder
Patients with cardiac disease or chronic kidney disease
All neuropathies
coagulopathies
patient refusal for spinal anaesthesia
Failed spinal
inadequate level of block
high spinal
prolonged surgery
Patient with allergic to the drug
Patient who are already on Pregabalin or Gabapentin
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the intensity of postoperative pain in 3 groups by numeric pain intensity scale (NPIS) for 24 hours.Timepoint: postoperative period
- Secondary Outcome Measures
Name Time Method To assess the sedation score of the drugTimepoint: intraoperative and postoperative peroid;To compare the time interval between subarachnoid block and first rescue analgesicTimepoint: from intraoperative peroid till postoperative peroid;To evaluate the presence of any adverse effects of drug (diplopia, nausea, vomiting, diarrhoea, confusion, respiratory depression).Timepoint: intraoperative and postoperative peroid;To evaluate total dosage of rescue analgesics given in first 24 hours.Timepoint: postoperative period