Indole-3-Carbinol Effects on Estrogen Metabolism

Phase 2

Terminated

• Conditions: Obesity
• Interventions: Dietary Supplement: Indole-3-carbinol

• Registration Number: NCT00988845
• Lead Sponsor: University of Wisconsin, Madison

Brief Summary

This study will test a dietary supplement, indole-3-carbinol, for improving the estrogen profile in women across a range of body mass index.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-09
• Study First Submitted: 2009-10-01
• Study First Submitted QC: 2009-10-01
• Study First Posted: 2009-10-02
• Primary Completion: 2010-07
• Study Completion: 2014-01
• Status Verified: 2015-04
• Last Update Submitted: 2019-12-12
• Last Update Posted: 2019-12-13

Recruitment & Eligibility

• Status: TERMINATED
• Sex: Female
• Target Recruitment: 38

Inclusion Criteria

• woman aged from 30 - 50 years
• regular menstrual cycle

Exclusion Criteria

• taking hormone replacement or hormonal contraception
• thyroid disorder
• uncontrolled asthma
• BMI under 18.5
• allergy to cruciferous vegetables

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Indole-3-carbinol	Indole-3-carbinol	-

Primary Outcome Measures

Name	Time	Method
Change in urinary 2/16-hydroxyestrone ratio	8 weeks

Trial Locations

Locations (1)

University of Wisconsin; 🇺🇸 Madison, Wisconsin, United States