Perioperative esmolol infusion for haemodynamic stability during major vascular surgery. - Perioperative esmolol infusio
- Conditions
- cardiac complications during and after vascular surgeryMedDRA version: 12.1Level: LLTClassification code 10028601Term: Myocardial ischemia
- Registration Number
- EUCTR2010-021844-17-NL
- Lead Sponsor
- Erasmus Medical Centre
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- All
- Target Recruitment
- Not specified
Patients are eligible for inclusion for the study at the Erasmus Medical Centre if they are:
1. Scheduled for arterial vascular surgery, including abdominal aortic aneurysm repair, abdominal aortic stenosis surgery, lower limb arterial reconstruction or carotid artery stenosis repair
2. Provide informed consent
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) no
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Potential subjects will be excluded with any of the following:
1. Active bleeding
2. Untreated left main disease
3. Active cardiac condition such as unstable angina pectoris, active congestive heart failure, serious cardiac arrhythmias, symptomatic valvular disease, recent MI< 6 months.
4. Preoperative positive troponin T
5. Contraindication for esmolol use
6. Previous allergy or intolerance to esmolol
7. Cancer with an expected life expectancy < 6 months
8. Excessive alcohol use
9. Pregnancy or planning to become pregnant
10. Failure to provide informed consent
11.Failure to monitor heart rate with the continuous 12-lead electrocardiography because of surgery or baseline electrocardiographic abnormalities.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method