Perioperative esmolol infusion for haemodynamic stability during major vascular surgery. - Perioperative Esmolol Infusion

Erasmus MC, Universitair Medisch Centrum Rotterdam0 个研究点目标入组 260 人开始时间: 待定最近更新: 2024年8月19日

适应症

试验速览

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•Patients are eligible for inclusion for the study at the Erasmus Medical Centre if they are:
•1. Scheduled for arterial vascular surgery, including abdominal aortic aneurysm repair, abdominal aortic stenosis surgery, lower limb arterial reconstruction or carotid artery stenosis repair
•2. Provide informed consent

•Potential subjects will be excluded with any of the following:
•1. Active bleeding
•2. Untreated left main disease
•3. Active cardiac condition such as unstable angina pectoris, active congestive heart failure, serious cardiac arrhythmias, symptomatic valvular disease, recent MI< 6 months.
•4. Preoperative positive troponin T
•5. Contraindication for esmolol use
•6. Previous allergy or intolerance to esmolol
•7. Cancer with an expected life expectancy < 6 months
•8. Excessive alcohol use
•9. Pregnancy or planning to become pregnant
•10. Failure to provide informed consent
•11.Failure to monitor heart rate with the continuous 12-lead electrocardiography because of surgery or baseline electrocardiographic abnormalities.

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