NL-OMON28827
Recruiting
Not Applicable
Esophageal epithelial permeability changes in patients with eosinophilic esophagitis.
Academic Medical Center, Amsterdam, The Netherlands0 sites16 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Eosinophilic esophagitis, pathophysiology, etiology, epithelial barrier integrity, permeability.Eosinofiele oesofagitis, pathofysiologie, etiologie, epitheliale barrierefunctie, permeabiliteit.
- Sponsor
- Academic Medical Center, Amsterdam, The Netherlands
- Enrollment
- 16
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
/A
Investigators
Eligibility Criteria
Inclusion Criteria
- •Eosinophilic esophagitis group:
- •1\. Previous diagnosis of EoE confirmed by histopathology e.g. presence of \>15 eosinophilic granulocytes per high power field (hpf) in mid\-esophageal biopsies before the start of any therapy;
Exclusion Criteria
- •Eosinophilic esophagitis group:
- •1\. Inability to stop topical corticosteroids;
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
Oesophageal epithelial permeability changes in patients with eosinophilic oesophagitisidiopathic allergic oesophagitis1001796910001708NL-OMON36166Academisch Medisch Centrum22
Not yet recruiting
Not Applicable
In vivo evaluation of esophageal mucosal permeability in patients with non erosive reflux diseaseGastro-esophageal reflux disease (GERD)heartburn10017977NL-OMON32964Academisch Medisch Centrum50
Completed
Not Applicable
Characterisation of esophageal epithelial damage in patients with non-erosive reflux disease (NERD) and erosive esophagitis (EE): role of epithelial permeabilityGERDreflux disease10017969NL-OMON37810Medisch Universitair Ziekenhuis Maastricht35
Completed
Phase 1
Intestinal Permeability in Response to Treatment in Eosinophilic Esophagitis PatientsEosinophilic EsophagitisNCT01641913Mayo Clinic20
Completed
Not Applicable
Impact of impaired barrier function of esophageal squamous epithelium by acetaldehyde and ethanol on carcinogenesis of esophageal squamous cell carcinoma (ESCC)Superficial esophageal carcinomaJPRN-UMIN000033164Tohoku University Graduate School of Medicine40