NL-OMON36166
已完成
不适用
Oesophageal epithelial permeability changes in patients with eosinophilic oesophagitis - Oesophageal epithelial permeability changes in EoE
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- idiopathic allergic oesophagitis
- 发起方
- Academisch Medisch Centrum
- 入组人数
- 22
- 状态
- 已完成
- 最后更新
- 去年
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •1\. Previous diagnosis of eosinophilic oesophagitis confirmed by histopathology e.g. presence of \>15 eosinophilic granulocytes per high power field in mid\-oesophageal biopsies before the start of any therapy
- •2\. Written informed consent
- •3\. Age 18 \* 75 years
排除标准
- •1\. Inability to stop topical corticosteroids
- •2\. Inability to stop PPI, H2\-receptor antagonist or prokinetic drug for 8 weeks
- •3\. Use of systemic corticosteroids, leukotriene inhibitors, or monoclonal antibodies, in the 2 month period preceding the study
- •4\. Use of oral anticoagulants
- •5\. Use of NSAIDs
- •6\. History of peptic ulcer disease
- •7\. History of Barrett\*s oesophagus
- •8\. History of GI cancer
- •9\. History of GI tract surgery (except appendectomy)
结局指标
主要结局
未指定
相似试验
招募中
不适用
Esophageal epithelial permeability changes in patients with allergic esophagitis.Eosinophilic esophagitis, pathophysiology, etiology, epithelial barrier integrity, permeability.Eosinofiele oesofagitis, pathofysiologie, etiologie, epitheliale barrierefunctie, permeabiliteit.NL-OMON28827Academic Medical Center, Amsterdam, The Netherlands16
尚未招募
不适用
In vivo evaluation of esophageal mucosal permeability in patients with non erosive reflux diseaseGastro-esophageal reflux disease (GERD)heartburn10017977NL-OMON32964Academisch Medisch Centrum50
已完成
不适用
Impact of impaired barrier function of esophageal squamous epithelium by acetaldehyde and ethanol on carcinogenesis of esophageal squamous cell carcinoma (ESCC)Superficial esophageal carcinomaJPRN-UMIN000033164Tohoku University Graduate School of Medicine40
尚未招募
不适用
Assessing the efficacy of Resection and Plication (RAP) on oesophageal physiology and symptoms in patients with gastro-oesophageal reflux disease (GORD).gastro-oesophageal reflux disease (GORD)Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colonACTRN12624001189516Dr Calvin Park10
已完成
不适用
Characterisation of esophageal epithelial damage in patients with non-erosive reflux disease (NERD) and erosive esophagitis (EE): role of epithelial permeabilityGERDreflux disease10017969NL-OMON37810Medisch Universitair Ziekenhuis Maastricht35