跳至主要内容
临床试验/NL-OMON36166
NL-OMON36166已完成不适用

Oesophageal epithelial permeability changes in patients with eosinophilic oesophagitis - Oesophageal epithelial permeability changes in EoE

Academisch Medisch Centrum0 个研究点目标入组 22 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
22

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 99(—)

入选标准

  • 1. Previous diagnosis of eosinophilic oesophagitis confirmed by histopathology e.g. presence of >15 eosinophilic granulocytes per high power field in mid-oesophageal biopsies before the start of any therapy
  • 2. Written informed consent
  • 3. Age 18 * 75 years

排除标准

  • 1. Inability to stop topical corticosteroids
  • 2. Inability to stop PPI, H2-receptor antagonist or prokinetic drug for 8 weeks
  • 3. Use of systemic corticosteroids, leukotriene inhibitors, or monoclonal antibodies, in the 2 month period preceding the study
  • 4. Use of oral anticoagulants
  • 5. Use of NSAIDs
  • 6. History of peptic ulcer disease
  • 7. History of Barrett*s oesophagus
  • 8. History of GI cancer
  • 9. History of GI tract surgery (except appendectomy)

研究者

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