The impact of Goal-Directed Prehabilitation Therapy on the functional capacity in patients undergoing highly invasive surgery. A randomized controlled study
Not Applicable
- Conditions
- Patients who are going to undergo a highly invasive abdominal surgery.
- Registration Number
- JPRN-UMIN000038791
- Lead Sponsor
- agoya University Graduate School of Medicine, Division of Gastrointestinal Surgery, Department of Surgery
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 180
Inclusion Criteria
Not provided
Exclusion Criteria
Patients who rejected to participate this study. who can not do exercise. who has a congenital metabolic disorder for the branched chain amino acids. who undergo emergent surgery. who are with severe complications. who are with mental disorder. who are with cognitive disorder. who have a risk of fall. who are not eligible for the study determined by the investigators.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the nutritional status, host immune function, intestinal microbitota, fecal organic acids concentrations, muscle mass, fat mass, and exercise capacity between conventional prehabilitation group and goal-directed prehabilitation group.
- Secondary Outcome Measures
Name Time Method 1. To Compare the incidence of postoperative complications and the length of postoperative hospital stay. 2.To investigate the correlation between the preoperative conditions including nutritional status, host immune function, intestinal microbiota, fecal organic acids concentrations, muscle mass, fat mass, and functional exercise capacity and the incidence of postoperative complications and the length of postoperative hospital stay. 3.To compare the long term outcome after surgery between Synbiotics and Synbio-Prehabilitation groups. 4.To investigate the impact of preoperative nutritional status, host immune function, intestinal microbiota, fecal organic acids, muscle mass, fat mass, and functional exercise capacity on the long term outcome after surgery.