An Electronic Alert System for In-Hospital Acute Kidney Injury

Not Applicable

Completed

• Conditions: Acute Kidney Injury
• Interventions: Other: Alert

• Registration Number: NCT01862419
• Lead Sponsor: University of Pennsylvania

Brief Summary

This study will randomize hospitalized patients with acute kidney injury (AKI) to usual care, or an electronic alert intervention. The electronic alert will be in the form of a text page that will be sent to the covering clinician and unit pharmacist once per patient with AKI at the time lab results are uploaded. The investigators hypothesize that such an alert will improve outcomes in these patients.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study First Submitted: 2013-05-16
• Study First Submitted QC: 2013-05-21
• Study First Posted: 2013-05-24
• Study Start: 2013-09
• Status Verified: 2014-04
• Primary Completion: 2014-04
• Study Completion: 2014-04
• Results First Submitted: 2015-03-13
• Results First Submitted QC: 2015-03-13
• Last Update Submitted: 2015-03-13
• Results First Posted: 2015-03-25
• Last Update Posted: 2015-03-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2393

Inclusion Criteria

• Adults >=18 years
• Admitted to the Hospital of the University of Pennsylvania for greater than 24 hours.

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Exclusion Criteria

• Dialysis order within 24 hours of admission
• Dialysis order prior to AKI onset
• Initial creatinine >=4.0mg/dl
• Prior admission in which patient was randomized.
• Nephrectomy during the admission
• Admission to hospice service
• Admission to observation status

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Alert	Alert	Text page sent to patient's covering provider and unit pharmacist informing them of the presence of AKI as detected by changes in serum creatinine.

Primary Outcome Measures

Name	Time	Method
Dialysis Within 7 Days	From start of AKI to 7 days later	This metric will be sequentially ranked. The provision of acute dialysis therapy will be ranked as a more severe outcome than the worst relative change in creatinine and death will be ranked as a more severe outcome than dialysis.
Death	7 days of randomization
Relative Maximum Change in Creatinine	7 days of randomization

Trial Locations

Locations (1)

Hospital of the University of Pennsylvania; 🇺🇸 Phiadelphia, Pennsylvania, United States