An Electronic Alert System for In-Hospital Acute Kidney Injury: A Randomized, Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 2,393
- 试验地点
- 2
- 主要终点
- Death
研究概览
简要总结
This study will randomize hospitalized patients with acute kidney injury (AKI) to usual care, or an electronic alert intervention. The electronic alert will be in the form of a text page that will be sent to the covering clinician and unit pharmacist once per patient with AKI at the time lab results are uploaded. The investigators hypothesize that such an alert will improve outcomes in these patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults >=18 years
- •Admitted to the Hospital of the University of Pennsylvania for greater than 24 hours.
排除标准
- •Dialysis order within 24 hours of admission
- •Dialysis order prior to AKI onset
- •Initial creatinine >=4.0mg/dl
- •Prior admission in which patient was randomized.
- •Nephrectomy during the admission
- •Admission to hospice service
- •Admission to observation status
结局指标
主要结局
Death
时间窗: 7 days of randomization
Dialysis Within 7 Days
时间窗: From start of AKI to 7 days later
This metric will be sequentially ranked. The provision of acute dialysis therapy will be ranked as a more severe outcome than the worst relative change in creatinine and death will be ranked as a more severe outcome than dialysis.
Relative Maximum Change in Creatinine
时间窗: 7 days of randomization
次要结局
未报告次要终点