An Electronic Alert System for In-Hospital Acute Kidney Injury: A Randomized, Controlled Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute Kidney Injury
- Sponsor
- University of Pennsylvania
- Enrollment
- 2393
- Locations
- 1
- Primary Endpoint
- Death
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
This study will randomize hospitalized patients with acute kidney injury (AKI) to usual care, or an electronic alert intervention. The electronic alert will be in the form of a text page that will be sent to the covering clinician and unit pharmacist once per patient with AKI at the time lab results are uploaded. The investigators hypothesize that such an alert will improve outcomes in these patients.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Adults \>=18 years
- •Admitted to the Hospital of the University of Pennsylvania for greater than 24 hours.
Exclusion Criteria
- •Dialysis order within 24 hours of admission
- •Dialysis order prior to AKI onset
- •Initial creatinine \>=4.0mg/dl
- •Prior admission in which patient was randomized.
- •Nephrectomy during the admission
- •Admission to hospice service
- •Admission to observation status
Outcomes
Primary Outcomes
Death
Time Frame: 7 days of randomization
Dialysis Within 7 Days
Time Frame: From start of AKI to 7 days later
This metric will be sequentially ranked. The provision of acute dialysis therapy will be ranked as a more severe outcome than the worst relative change in creatinine and death will be ranked as a more severe outcome than dialysis.
Relative Maximum Change in Creatinine
Time Frame: 7 days of randomization