The Effect of Automated Electronic Alert for Acute Kidney Injury on the Outcomes of Hospitalized Patients: a Single Center Randomized Controlled Trial.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 4,536
- 试验地点
- 1
- 主要终点
- Estimated glomerular filtration rate changed within 7 days
研究概览
简要总结
Acute kidney injury (AKI) is a common disease, but diagnosis is usually delayed or missed in hospitalized patients. The automated electronic alert for AKI may help to improve the outcomes of these patients through identifying all cases of AKI early. Therefore, the investigators conduct a randomly controlled study to test whether automated electronic alert for AKI could improve the outcomes of hospitalized patients.
详细描述
Acute kidney injury (AKI) is a common disease, but diagnosis is usually delayed or missed in hospitalized patients. The automated electronic alert for AKI may help to improve the outcomes of these patients through identifying all cases of AKI early. Therefore, the investigators conduct a randomly controlled study to test whether automated electronic alert for AKI could improve the outcomes of hospitalized patients.
The patients were randomly divided into two groups:
Usual care : patients will receive standard clinical care by the primary physicians AKI alert : an AKI alert will be sent to the doctor in charge. The team of kidney experts would give a suggestion if the doctor in charge need a renal consultation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Double (Participant, Outcomes Assessor)
盲法说明
All study investigators and participants were blinded to patients randomization status.
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hospitalized adult patients with an Alert for AKI(based on KDIGO guidelines)
排除标准
- •Patients already having eGFR<15ml/min/1.73m2 or receiving renal replacement therapy for AKI at the time of alert.
- •Patients already having a AKI before admission.
结局指标
主要结局
Estimated glomerular filtration rate changed within 7 days
时间窗: within 7 days diagnosed with AKI
Medical record
次要结局
- receiving renal replacement therapy at 30th day(30 days)
- the rate of stage 3 AKI(within 7 days diagnosed with AKI)
- receiving renal replacement therapy at seventh day(7 days)
- Follow-up rate after discharge(1 year)
- seven-day mortality(within 7 days diagnosed with AKI)
- the interventions for AKI(within 7 days diagnosed with AKI)
- 30-day mortality(within 30 days diagnosed with AKI)
- receiving renal replacement therapy at 1 year(1 year)
- the rate of stage 2 AKI(within 7 days diagnosed with AKI)
- 1-year mortality(within 1 year diagnosed with AKI)
- the rate of AKI recovery at 90 day(90 days)
- the rate of timely-recognition of AKI(3 days)