Evaluate and compare the effects of intravenous dexmedetomidine andmagnesium sulphate as adjunct to general anesthesia on perioperative haemodynamicsvariability in patient undergoing laparoscopic cholecystectomy

Pt B. D. Sharma University Of Health Sciences, PGIMS,Rohtak, Haryana0 个研究点目标入组 69 人开始时间: 待定最近更新: 2024年3月4日

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•American society of Anesthesiology grade I and II between the age of 18-65 years, of either sex and posted for laparoscopic cholecystectomy under general anaesthesia

•Patients with major hepatic, renal and endocrine dysfunction, cardiovascular dysfunction; neuromuscular, neurological disorder, atrioventricular conduction disturbance, COPD, asthma, obstructive sleep apnea and haematological disorders.
•Patients with difficult airway.
•Patients with known allergy to dexmedetomidine or magnesium sulphate.
•Pregnancy, obesity (body mass index >30 kg m-2), hypertension, diabetes mellitus, and
•major systemic illness
•Patients on treatment with calcium channel blockers, beta-blockers, alpha 2 adrenergic agonists or
•opioid abuse
•Any intraoperative surgical complication like prolonged surgery (duration more than
•two hours) or conversion to open surgery,
•Patient’s unwillingness to participate in the study

发起方

Pt B. D. Sharma University Of Health Sciences, PGIMS,Rohtak, Haryana