Feasibility of Combined CT Colonography and PET Imaging for Detection of Colonic Involvement by Mantle Cell Lymphoma
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 主要终点
- Number of Participants with PET/CT Scan Detection of Mantle Cell Lymphoma
研究概览
简要总结
The goal of this clinical research study is to learn if positron emission tomography (PET)/computed tomography (CT) scanning can be used to detect mantle cell lymphoma in the colon. Researchers want to learn if PET/CT scanning can produce good-quality images and/or find the exact locations of lymphoma in the body.
Primary Objective is to determine if combined CT colonography and full body PET scan is technically feasible and can produce diagnostic scans as well as accurate anatomic coordination for detection of mantle cell lymphoma involvement of the colon.
详细描述
Colonoscopy Testing:
A colonoscopy is a routine test where the doctor looks at the inner lining of the colon using a long, flexible, lighted tube that is inserted through the anus. This is the standard procedure for detecting mantle cell lymphoma in the colon.
PET/CT Scanning:
Because PET/CT scanning is less invasive than colonoscopy, researchers want to learn more about whether PET/CT scanning may be able to be used for detecting mantle cell lymphoma in the colon.
PET/CT scanning is also considered a routine test for checking the status of mantle cell lymphoma. The scan is called "full body" because the neck, chest, abdomen (stomach area), and pelvis are included.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who have newly diagnosed mantle cell lymphoma who are already scheduled for standard PET/CT and colonoscopy as part of their staging.
- •Adults (>18 years of age)
排除标准
- •Known diabetes
- •Known complete colonic obstruction
- •Known small bowel obstruction
- •Known anorectal stenosis or acute inflammatory disease or rectal prolapse.
- •Active colitis or diverticulitis
- •Known radiation in the last 2 weeks
- •Known endoscopic hot forceps biopsy in the last 2 weeks
- •Known rectal incontinence
- •Tachypnea or respiratory distress
- •Known end or loop colostomy or ileostomy
- •Contraindications to colonoscopy, including bleeding diathesis; contraindications to sedation because of allergy or respiratory compromise.
- •Patients who are pregnant
- •Diarrhea within the past week
- •Currently participating in chemotherapy treatment
结局指标
主要结局
Number of Participants with PET/CT Scan Detection of Mantle Cell Lymphoma
时间窗: 1 Day, Participation completed day of CT colonography and full body PET scan
次要结局
- Number of PET/CT Scanning Images Locating Exact Lymphoma Locations(2 years)