V flow patterns in systolic heart failure: A new aspect elucidated by high-frame rate echocardiography (PHRAsE study)

Recruiting

• Conditions: heart failure; systolic dysfunction; 10019280

• Registration Number: NL-OMON50390
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 120

Inclusion Criteria

In order to be eligible to participate in this study, a subject must meet all
of the following criteria:
* aged * 18 years;
* capable of understanding and signing informed consent.
* Patients with known heart failure with or without CRT, or heart valve
pathology
* Sub-study: 30 patients with heart failure and no CRT who also undergo
cardiac MRI for clinical routine

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded
from participation in this study:
* Patients living abroad or who are not Dutch speaking.
* Any contra-indication for contrast media Sonovue (Bracco International bv,
Amsterdam).
* Patients with significant ventricular arrhythmia, acute coronary syndrome, or
coronary revascularization within 6 months before CRT are excluded
* Patients with inability to obtain adequate echocardiographic examination will
be excluded.
* Patients with a contraindication for MRI (i.e. claustrophobia) or contrast
agent (eGFR <30 ml/min or allergy)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified