The Role of Pulsed Dye Laser Therapy in the Management of Burn Scars

Not Applicable

Recruiting

• Conditions: Burn Scar
• Interventions: Procedure: pulsed dye laser

• Registration Number: NCT01488240
• Lead Sponsor: University of Manitoba

Brief Summary

The purpose of this study is to determine the effects (good or bad) of pulsed dye laser treatment in burn scar height, texture, redness and pliability in acute burn injury.

Detailed Description

While the literature tends to support the use of laser therapy in the management of burn scars, there is a definite lack of appropriately powered, randomized controlled trials. Laser therapy can be quite expensive when compared to other treatment modalities for burn scars, and while promising, its true usefulness has yet to be conclusively demonstrated. For this reason, our research group is proposing the commencement of two randomized controlled trial pilot studies assessing the effects of pulsed dye laser (PDL) on burn scars. The objectives of this project will be to determine the effectiveness of pulsed dye laser therapy on burn scar vascularity, pliability, height and texture. It has been hypothesized that the PDL works on acute injury to decrease scar formation, and the fractional laser works on scar that is quiescent to promote remodelling. Therefore the investigators are proposing to study both acute injury and late burn scars. This project will compare the effects of each laser type, and will either help support or refute the assertion that laser therapy can be used to improve burn scars.

Objectives:

To determine the benefit of pulsed dye laser treatment in improving burn scar height, texture, vascularity and pliability in acute burn injury.

Study Timeline

• Study First Submitted: 2011-12-05
• Study First Submitted QC: 2011-12-07
• Study First Posted: 2011-12-08
• Study Start: 2012-11-01
• Status Verified: 2024-12
• Last Update Submitted: 2024-12-03
• Last Update Posted: 2024-12-05
• Primary Completion: 2026-06-01
• Study Completion: 2027-06-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 6

Inclusion Criteria

• burn scar
• living in Winnipeg
• scar age one to 6 months
• Fitzpatrick I-III skin type

Exclusion Criteria

• open wound
• active infection
• previous scar treatment with steroid injection or interferon
• established disposition towards keloid scarring

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Distal	pulsed dye laser	part of scar distal to heart
Proximal	pulsed dye laser	part of scar proximal to heart

Primary Outcome Measures

Name	Time	Method
Scar Characteristics	six months	Examine characteristics of scar

Trial Locations

Locations (1)

University of Manitoba; 🇨🇦 Winnipeg, Manitoba, Canada