Comparison between Pethidine and Dipyrone as Analgesics during Labor
- Conditions
- M01.975O75.0Pain, Maternal Suffering during labor, womenC10.597.617
- Registration Number
- RBR-4hsyy4
- Lead Sponsor
- IFOR - Universidade de Fortaleza
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Data analysis completed
- Sex
- Female
- Target Recruitment
- Not specified
Presence of at least 3 uterine contractions lasting 40 seconds or more every 10 minutes; Patients presenting a dilation of the uterine cervix equal to or greater than 5 cm; Measurement of pain through the use of visual analogue scale equal to or greater than 8; Gestational age of 37 up to 40 weeks and 6 days; Fetuses in cephalic presentation
Parturients with any of the following events: poorly controlled arterial hypertension, diabetes, restricted intrauterine growth and placental abruption; Use of oxitocyn by pregnant women in the period from the begining of labor until 2 hours after administration of the analgesic; Hypothyroidism diagnosed previously and without therapy; Patients taking monoamine oxidase inhibitors; Occurrence of labor less than 1 hour after analgesia; Parturients with body mass greater than 100 kg; Indication of cesarean delivery during admission; Addison's disease previously diagnosed; BCF's < 110 bpm, during admission; BCF's > 160 bpm, during admission; Patients allergic to sodium dipyrone; Patients allergic to pethidine; Users of chlorpromazine; Phenobarbital users; Phenytoin users; Fetus without vilality; Twin pregnancy; Drug addiction
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Expected outcome 1. One of the drugs was expected to show superior analgesic potency during labor. The avaluations were carried out between 5/20/2016 and 12/31/2016 ;Found outcome 1. The pain was measured by the visual analog scale just before the intervention, 1 hour and 2 hours after the intervention. Statistical evaluation was done using Student's t-test, ranging up to 1 standard deviation for more or less, at a significance of 5% and a 95% confidence interval. Similar analgesic effect occurred with the 2 drugs 1 hour after the intervention. One hour after the intervention, the score attributed to pain in participants who used Dipirone was 7.97 ± 1.226 and after Pethidine was 8.04 ± 1.271, with a p-value of 0.697. Two hours after the intervention, the two drugs did not present a statistically significant analgesic effect. The avaluations were carried out between 5/20/2016 and 12/31/2016
- Secondary Outcome Measures
Name Time Method