临床试验/NCT00000331

NCT00000331撤回2 期

Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-3

University of Colorado, Denver1 个研究点分布在 1 个国家开始时间: 2002年12月最近更新: 2017年5月4日

适应症

干预措施

试验速览

阶段: 2 期
状态: 撤回
发起方: University of Colorado, Denver
试验地点: 1
主要终点: Observed withdrawal rating

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The purpose of this study is to assess the abuse liability and examine the reinforcing effects of intravenous buprenorphine and buprenorphine/naloxone combinations in healthy, non-drug dependent volunteers.

详细描述

not available at this time

研究设计

研究类型: Interventional
主要目的: Treatment
盲法: Double

入排标准

年龄范围: 18 Years 至 65 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Individuals must be healthy, non-drug dependent volunteers, be at least 18 years of age, and have no prior history of drug or alcohol abuse or dependence. Subjects must have had some minimal experience with opioids (e.g. at least two prior exposures)

排除标准

•Individuals with evidence of an active Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) Axis I psychiatric disorder (e.g. psychosis, manic-depressive illness, organic psychiatric disorders), significant medical illness (e.g., liver or cardiovascular disease) or pregnant female subjects are excluded from study participation.

研究组 & 干预措施

Test Drug

Experimental

Test drug to prevent heroine withdrawal

干预措施: Test Drug (Drug)

Placebo Pill

Placebo Comparator

Placebo drug

干预措施: Placebo Drug (Drug)

结局指标

主要结局

Observed withdrawal rating

Drug effect characteristics

Pupil diameter

次要结局

未报告次要终点

研究者

发起方

University of Colorado, Denver

申办方类型

Other

责任方

Sponsor

研究点 (1)

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