NCT00000330撤回2 期
Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-2
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 撤回
- 试验地点
- 2
- 主要终点
- Observed withdrawal rating
研究概览
简要总结
The purpose of this study is to assess the abuse liability and reinforcing effects of intravenous buprenorphine and buprenorphine/naloxone combinations in heroin-dependent volunteers
详细描述
not available at this time
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Individuals must be at least 18 yrs of age, currently opioid dependent and must not be seeking treatment. Co-morbid substance abuse or dependence disorders may also be present. Individuals must be healthy despite drug dependency and have a history of IV opioid use.
排除标准
- •Individuals with evidence of an active Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) Axis I psychiatric disorder (e.g. psychosis, manic-depressive illness, organic psychiatric disorders), significant medical illness (e.g. liver or cardiovascular disease) or pregnant female subjects are excluded from study participation.
结局指标
主要结局
Observed withdrawal rating
Pupil diameter
Opioid antagonist rating
Drug effect characteristics
Drug/Money Preferences
Subjective dose estimate
Analog rating scale for drug effects
次要结局
未报告次要终点
研究者
研究点 (2)
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