NCT00000329撤回2 期
Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-1
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 撤回
- 试验地点
- 2
- 主要终点
- Drug/Money Preferences
研究概览
简要总结
The purpose of this study is to assess the abuse liability and examine the reinforcing effects of intravenous buprenorphine and buprenorphine/naloxone combinations in buprenorphine-naloxone maintained volunteers
详细描述
Ongoing study - results not available at this time
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Individuals must be at least 18 yrs of age, currently opioid dependent and meet FDA criteria for narcotic maintenance treatment. Co-morbid substance abuse or dependence disorders may also be present. Individuals must be healthy despite drug dependency and have a history of IV opioid use.
排除标准
- •Individuals with evidence of anti active Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) Axis I psychiatric disorder (e.g. psychosis, manic-depressive illness, organic psychiatric disorders), significant medical illness (e.g. liver or cardiovascular disease) or pregnant female subjects are excluded from study participation.
结局指标
主要结局
Drug/Money Preferences
Subjective dose estimate
Observed withdrawal rating
Opioid agonist rating
Opioid antagonist rating
Analog rating scale for drug effects
Pupil diameter
Drug effect characteristics
次要结局
未报告次要终点
研究者
研究点 (2)
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