A Comparative Study Between Intrathecal Dexmedetomidine VS Ketamine With Intrathecal Bupivacaine in Orthopedic Lower Limb Surgeries.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- comparison between duration of analgesia from Ketamine Vs Dexmedtomidine in the Patients with lower limb surgery
研究概览
简要总结
Orthopedic anaesthesia and acute postoperative pain management, two anesthesiology subspecialties,are getting more credit for reducing hospital stays, promoting functional recovery and improving patient satisfaction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •The study will include 100 adult patients (18 to 50 years old) with ASA physical status class I and class II undergoing orthopedic lower limb surgeries under itrathecal anathesia .
排除标准
- •Patient refusal.
- •Drug abuse.
- •Patient with neurological, psychiatric or neuromuscular disease.
- •Chronic pain on medicine.
- •Known allergy to the study medications.
- •Patients e contraindications to intrathecal anesthesia .
研究组 & 干预措施
Group D
(50 patients) will receive calculated dose of intrathecal hyperbaric bupivacaine 0.5 % according to body weight and 5μg dexametomidine.
干预措施: Dexmedetomidine (Drug)
Group K
(50 patients) will receive calculated dose of intrathecal hyperbaric bupivacaine 0.5 % according to body weight and 0.1 mg/kg ketamine.
干预措施: Ketamine (Drug)
结局指标
主要结局
comparison between duration of analgesia from Ketamine Vs Dexmedtomidine in the Patients with lower limb surgery
时间窗: 1 year
comparison between duration of analgesia from Ketamine Vs Dexmedtomidine in the Patients with lower limb surgery.
次要结局
未报告次要终点
研究者
Ziad Ahmed Ali
A comparative study between intrathecal dexmedetomidine VS ketamine with intrathecal bupivacaine in orthopedic lower limb surgeries.
Sohag University