The influence of MAC values and behaviour of a child on emergence delirium after sevoflurane anesthesia

Recruiting

• Conditions: postoperatieve gedragsstoornissen na sevoflurane anesthesie; emergence delirium; 10012221

• Registration Number: NL-OMON39079
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 110

Inclusion Criteria

age between 1,5-6 years
children scheduled for MRI scan onder general anesthesia
no premedication
ASA status 1-2
parents who speak Dutch
parents present during anesthesia induction
written informed consent

Exclusion Criteria

Risk of malignant hyperthermia
Hypersensitivity to sevoflurane or propofol
Need for premedication

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary research question:<br /><br><br /><br>Is it possible that adapting the amount of sevoflurane, from 1 MAC (2,5 vol%)<br /><br>to * MAC (1,25 vol%) in an MRI scan can reduce the frequency and gravity of ED?</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary research question:<br /><br><br /><br>Do the anxiety of the parents (measured by the APAIS), the anxiety of the child<br /><br>at induction (measured by the m-YPAS) and the behaviour (measured by the CBCL<br /><br>11/2-5) constitute a predictive value for the appearance of ED (measured with<br /><br>the PAED scale)?<br /><br><br /><br>What is the incidence of application of escape medication (propofol) during the<br /><br>anaesthesia?</p><br>