'The frequency of behaviour disturbances after different concentration of anaesthetic gases (Sevoflurane) for anaesthesia during M.R.I. examination in children.
- Conditions
- Emergence delirium (ED) is described as a mental disorder during recovery from general anaesthesia. After the introduction of new inhalation anaesthetics such as Sevoflurane, this phenomenon again gained prominence. The specific cause is unknown. Anaesthesia, surgery and patient related factors are part of the possible explanations.
- Registration Number
- NL-OMON21231
- Lead Sponsor
- Department of Anaesthesia, Erasmus University Medical Centre Rotterdam, Sophia Childrenfs Hospital, Rotterdam Dr. Molewaterplein 603015 GJ Netherlands
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 110
Inclusion Criteria
1. Age between 1,5-5 years;
2. Written permission (informed consent);
Exclusion Criteria
1. Cognitive or emotional development disorder (with exception of attention deficit hyperactivity disorder (ADHD));
2. Use of active ingredients (AI) which influence the central nervous system (anticonvulsants);
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary endpoints are the maximum scores on the Pediatric Anesthesia Emergence Delirium Scale (PAED) until 1 hour after having stopped the administration of the anaesthetic. We consider a score of >12 on the PAED scale as cut-off for the presence or absence of ED.
- Secondary Outcome Measures
Name Time Method 1. The secondary endpoints are the time between terminating the administration and the removal of the laryngeal mask airway and the time of reaction (responsiveness) to light or gentle tactile stimulation;<br /><br>2. Are parents and childrens anxiety at induction, as well as their behaviour, a predictive value for the appearance of ED?