Depth of Anaesthesia monitoring- Isoflurane vs Sevoflurane
Phase 4
- Conditions
- Health Condition 1: N202- Calculus of kidney with calculus of ureterHealth Condition 2: N22- Calculus of urinary tract in diseases classified elsewhereHealth Condition 3: N186- End stage renal diseaseHealth Condition 4: O- Medical and Surgical
- Registration Number
- CTRI/2021/09/036403
- Lead Sponsor
- Dr Dy Patil Medical College Hospital and research center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA I and II
Exclusion Criteria
Patients on sedatives and hypnotics preoperatively
Hemodynamically unstable patients
Patients with altered sensorium
Patients with psychiatric illness and alcohol/substance abuse
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method BIS measurement at different MAC values(0.5,0.7,1,1.2,1.5) of Isoflurane <br/ ><br>BIS measurement at different MAC values (0.5,0.7,1,1.2,1.5) <br/ ><br>Hemodynamic monitoring at different MAC values of Isoflurane and Sevoflurane( Heart rate , Blood pressure and Mean arterial pressure)Timepoint: BIS measurement at different MAC values(0.5,0.7,1,1.2,1.5) of Isoflurane - <br/ ><br>BIS measurement at different MAC values (0.5,0.7,1,1.2,1.5) <br/ ><br>Hemodynamic monitoring at different MAC values of Isoflurane and Sevoflurane( Heart rate , Blood pressure and Mean arterial pressure) after 10 mins after each MAC value is achieved.Duration- 2 minutes prior to intubation till 5 minutes prior to extubation
- Secondary Outcome Measures
Name Time Method To figure out inhalation agent Sevoflurane vs Isoflurane with better hemodynamic stabilityTimepoint: BIS measurement and hemodynamic parameters (SBP,DBP,PR,MAP) 10 mins after each MAC is achieved ie( 0.5,0.7,1,1.2,1.5). Duration -10 minutes prior to the start of surgery till 24 hours post surgery to monitor any intraoperative awareness during Anesthesia