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Interest of a Standardized Monitoring of Rheumatoid Arthritis: The COMEDRA Trial

Not Applicable
Completed
Conditions
Rheumatoid Arthritis
Interventions
Behavioral: Auto-DAS
Behavioral: Comorbidities treatment
Registration Number
NCT01315652
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Brief Summary

The two objectives of this trial are :1 To evaluate the impact of a visit with a nurse checking the preventive modalities and/or the presence of comorbidities such as infections ( e.g. vaccinations), cardiovascular-diseases (e.g. Indication to statin, antiaggregant,anti-hypertensive treatment...), cancers (e.g.mammography,...), osteoporosis (e.g. bone densitometry,..) in patients suffering from Rheumatoid Arthritis 2 To evaluate the impact of an educational program aimed at permitting rheumatoid arthritis patients to auto-evaluate their disease activity by collecting the Disease Activity Score (DAS28-ESR).

Detailed Description

Patients with a stable definite Rheumatoid Arthritis will be invited by their rheumatologists to participate at this study in 20 centers in France. After written informed consent will be obtained, the patients will be randomized in two arms:

* comorbidities

* auto-DAS The patients will be seen again in the same center six months later in order to collect the outcome measures.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
970
Inclusion Criteria
  • Rheumatoid Arthritis
  • Stable (no change in therapy)
  • Adult
  • Able to collaborate

Exclusion criteria

  • Pregnant woman
  • Change of the therapy for 3 months before the inclusion
  • Alcoholism, toxicomania, psychological problem, sever co morbidity which could invalid the consent or limit the protocol compliance
  • No social coverage affiliate
Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Auto DASAuto-DAS"Auto-DAS"Number of patients with a modification in their treatment between baseline and 6 months visits
Comorbidities treatmentComorbidities treatment-
Primary Outcome Measures
NameTimeMethod
Comorbidities treatment6 months later

Number of actions initiated I order to treat or prevent Rheumatoid Arthritis comorbidities

Auto-DAS: Patient education to calculate his Disease Activity Score6 months after

Number of patients with a modification in their treatment between baseline and 6 months visits

Secondary Outcome Measures
NameTimeMethod
Frequency of comorbidities in Rheumatoid Arthritis6 months later
Adhesion to the current recommendations concerning the prevention of co-morbidities6 months later
Compliance and satisfaction of the patients concerning the DAS educational program6 months later

Trial Locations

Locations (1)

Hôpital Cochin

🇫🇷

Paris, France

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