Clinical relevance of HLA-specific memory B cells in kidney transplant recipients undergoing desensitizatio
Recruiting
- Conditions
- immunizationkidney transplantationniertransplantatatie
- Registration Number
- NL-OMON49890
- Lead Sponsor
- Inwendige Geneeskunde
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
- Adult kidney transplant recipients (>=18 years of age) receiving a kidney
transplantation in the Erasmus Medical Center
- Adult kidney transplant recipients who are HLA-incompatible with their kidney
donor, and who are defined as:
-either participating in the national referral program for desensitization for
HLA-incompatible living-donor kidney transplantation
-or receiving an HLA-incompatible deceased-donor via the Imlifidase
desensitization protocol
- able to give written informed consent
Exclusion Criteria
- below 18 years of age
- unable to give written informed consent
- previous treatment with Rituximab (CD20 monoclonal antibody) or any other
B-cell depleting therapy during the last 12 months.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method