The Effect of Pressure Controlled Volume Guaranteed Ventilation and Volume Controlled Ventilation on Hemodynamics and Lung Dynamics in Prone Position Patients in Thoracolomber Vertebra Surgery
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- Comparison of the effects of pressure controlled volume guaranteed ventilation and volume controlled ventilation on lung compliance
研究概览
简要总结
In this study, it was aimed to compare the effects of pressure-controlled volume-guaranteed ventilation (PCV-VG) and volume-controlled ventilation (VCV) on lung dynamics and hemodynamics in patients undergoing vertebral surgery in the prone position.
详细描述
The VCV (volume controlled ventilation) mode is the mode commonly used in general anesthesia practice. In VCV mode, the parameters under control are tidal volume and respiratory rate. In VCV mode, airway pressure changes depending on resistance and compliance. There is a risk of increased airway pressures in this mode.
In PCV-VG (pressure controlled volume guaranteed ventilation) mode, the parameters under control are the peak airway inspiratory pressure and the I/E ratio. It has been shown that peak airway pressures decrease and partial oxygen pressure increase due to decreased inspiratory flow in this ventilation mode.
Both ventilation modes are frequently used in patients undergoing general anesthesia.
In this study, it was aimed to compare the effects of pressure-controlled volume-guaranteed ventilation (PCV-VG) and volume-controlled ventilation (VCV) on lung dynamics (pulmonary peak-plateau pressure, compliance, driving pressure, SpO2 and end-tidal carbon dioxide) and hemodynamics (mean arterial pressure and heart rate) in patients undergoing vertebral surgery in the prone position.
In the study, patients will be randomized and divided into 2 groups after obtaining informed consent forms. If a mode change is required during the surgery, that patient will be excluded from the study.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients who will undergo thoracolumbar vertebral surgery in the prone position
- •Patients older than 18 years
- •Patients younger than 70 years of age
- •ASA 1-2 patients
排除标准
- •Patients with a BMI >30 kg/m2
- •Patients with a history of chronic pulmonary disease
- •Patients with a history of previous thoracic surgery
- •Patients with ASA >3
- •Patients who will undergo emergency surgery
- •Pregnant patients
结局指标
主要结局
Comparison of the effects of pressure controlled volume guaranteed ventilation and volume controlled ventilation on lung compliance
时间窗: 3 months
Comparison of the effects of pressure controlled volume guaranteed ventilation (PCV-VG) and volume controlled ventilation (VCV) on lung compliance (ml/cmH20) in patients undergoing vertebral surgery in a prone position
次要结局
- Comparison of the effects of pressure controlled volume guaranteed ventilation and volume controlled ventilation on heart rate(3 months)
- Comparison of the effects of pressure-controlled volume guaranteed ventilation and volume-controlled ventilation on mean arterial pressure(3 months)
研究者
Derya Arslan Yurtlu
Associate Professor
Izmir Ataturk Training and Research Hospital