Retinal Nerve Fibres Layers Thickness Study in Glaucomatous Patients

University of Roma La Sapienza1 site in 1 countryDecember 6, 2010

ConditionsGlaucoma

Drugsforskolin, rutin and vitamins B1 and B2

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Glaucoma
Sponsor: University of Roma La Sapienza
Locations: 1
Primary Endpoint: retinal nerve fibres layer thickness
Status: Completed
Last Updated: 15 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

In this study the investigators are going to study the retinal nerve fibers layers (RNFL) modification of two groups of patients, one taking no drugs, the other taking forskolin, rutin and vitamins B1 and B2.

Registry

clinicaltrials.gov

Start Date

December 6, 2010

End Date

TBD

Last Updated

15 years ago

Study Type

Interventional

Sex

All

Investigators

Sponsor

University of Roma La Sapienza

Eligibility Criteria

Inclusion Criteria

•Age (30-80 years);
•Baseline Intraocular pressure (IOP) (20-32 mmHg): average untreated Intra Ocular Pressure (IOP) for both eyes as determined from 2 to 4 visits within a 6-months period;
•Central Corneal Thickness (CCT) (475-650 µm): average of 3 different measurements from both eyes during the same visit;
•Pattern standard deviation (PSD) (0,50-3,00 dB) average of both eyes as stated on the most recent visual field index report
•Vertical Cup/Disk ratio (0,00-0,80): average of both eyes
•All these data were entered into a calculator specially designed for STAR (Scoring Tool for assessing risk) II parameter. The patients were divided into low-, moderate- and high risk groups according to the result given by the calculator.