Skip to main content
Clinical Trials/NCT01254006
NCT01254006CompletedNot Applicable

Retinal Nerve Fibres Layers Thickness Study in Glaucomatous Patients

University of Roma La Sapienza1 site in 1 countryStarted: December 6, 2010Last updated:
Conditions
Drugs

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Locations
1
Primary Endpoint
retinal nerve fibres layer thickness

Study Overview

Brief Summary

In this study the investigators are going to study the retinal nerve fibers layers (RNFL) modification of two groups of patients, one taking no drugs, the other taking forskolin, rutin and vitamins B1 and B2.

Study Design

Study Type
Interventional

Eligibility Criteria

Ages
30 Years to 80 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Age (30-80 years);
  • Baseline Intraocular pressure (IOP) (20-32 mmHg): average untreated Intra Ocular Pressure (IOP) for both eyes as determined from 2 to 4 visits within a 6-months period;
  • Central Corneal Thickness (CCT) (475-650 µm): average of 3 different measurements from both eyes during the same visit;
  • Pattern standard deviation (PSD) (0,50-3,00 dB) average of both eyes as stated on the most recent visual field index report
  • Vertical Cup/Disk ratio (0,00-0,80): average of both eyes
  • All these data were entered into a calculator specially designed for STAR (Scoring Tool for assessing risk) II parameter. The patients were divided into low-, moderate- and high risk groups according to the result given by the calculator.

Exclusion Criteria

  • other ocular pathologies than glaucoma

Outcomes

Primary Outcomes

retinal nerve fibres layer thickness

Secondary Outcomes

  • global risk threshold for glaucoma progression

Investigators

Sponsor
University of Roma La Sapienza
Sponsor Class
Other

Study Sites (1)

Loading locations...

Similar Trials

Retinal Nerve Fibres Layers Thickness... | Clinical Trial