Treatment with statin on atheroma regression evaluated by intravascular ultrasound with Virtual Histology; TRUTH Study (Kanagawa PTCA Conference Regression Study 5; KPCR5)
- Conditions
- Patients with stable or unstable angina
- Registration Number
- JPRN-C000000311
- Lead Sponsor
- Kanagawa PTCA Conference
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 160
Not provided
1)Patients currently medicated with statins or other lipid lowering therapy 2)Patients meeting the contraindications or relative contraindications for pitavastatin and pravastatin 3)Patients with hepatic disorder (AST or ALT greater than 2.5 times of the normal upper limits) 4)Patients with renal dysfunction (serum creatinine 2.0mg/dL or higher) 5)Patients with a history of severe muscular disorder or increased CK (CPK) greater than 2.5 times of the normal upper limit 6)Patients with acute myocardial infarction occurred within 24 hours 7)Patients failed to PCI 8)Patients with cerebrovascular accident occurred within 1 month 9)Patients with concurrent or a history of malignant disease within 5 years 10)Patients receiving LDL apheresis 11)Patients with homozygous familial hypercholesterolemia 12)Patients requiring the following prohibited concomitant drugs 13)Drug abusers 14)Patients participating in other studies 15)Patients ineligible for the study determined by physicians
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change of tissue characteristics in coronary plaque evaluated by intravascular ultrasound (IVUS) with Virtual Histology
- Secondary Outcome Measures
Name Time Method