NL-OMON50744已完成不适用
Metabolic state and survival in patients with amyotrophic lateral sclerosis - MEASURE
Afdeling Neurologie0 个研究点目标入组 234 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 234
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •For patients only (N = 78): meeting the El Escorial criteria for definite,
- •probable, probable laboratory supported or possible ALS, For controls only (N =
- •78): diagnosis with neurological syndrome within the range of peripheral
- •polyneuropathies with sensorimotor or motor fiber involvement. Or other motor
- •neuron disease (primary lateral sclerosis, progressive muscular atrophy,
- •progressive bulbar palsy or pseudobulbar palsy) , Asymptomatic carriers and
- •family members (N = 2x39): absence of any neurological symptom associated with
- •ALS., For family members, non-carriers and carriers, of any related gene to
- •ALS: absence of any neurological symtpoms associated with ALS. , All subjects:
- •>= 18 years of age
排除标准
- •All subjects:
- •1.2. Participants < 18 years of age
- •2.3. Participants are not able to lay down for at least one hour, without any
- •difficulties of swallowing or breathing.
- •3.4. Participants with tracheostomy or other assisted ventilation in the
- •preceding 3 months., Neurological Controls, asymptomatic carriers, carriers of
- •any other gene related to ALS and family members of ALS patients with a
- •suspected genetic background of ALS (familial ALS):
- •7.6. Patients with peripheral polyneuropathy with only sensory fiber
- •involvement (i.e. human immunodeficiency virus or vitamin B5 toxicity)
- •8.7. Patients with peripheral mononeuropathy (i.e. compression or entrapment
- •neuropathies)
研究者
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