Does oxygen when walking help to prevent muscle disease in patients with chronic obstructive pulmonary disease?

• Conditions: Chronic obstructive pulmonary disease; Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]

• Registration Number: EUCTR2011-003595-36-GB
• Lead Sponsor: niversity of Birmingham

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2012-04-26
• Last Update Posted: 4 August 2015

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

1) Spirometry: post bronchodilator FEV1/FVC <0.7 2) 6MWT: desaturation to less than 90% on walking 3) Blood gas: does not meet criteria for LTOT i.e. pO2 >7.3KPa or >8KPa if co-existent cor pulmonale
Are the trial subjects under 18? no
Number of subjects for this age range: 0
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 15
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 15

Exclusion Criteria

1) Immobile due to other medical conditions 2) On LTOT 3) Unable to understand or retain information 4) Uncontrolled anginal symptoms 5) Evidence of potential harm from oxygen supplementation on previous capillary gases or dejours test - specifically a rise in CO2 after being given oxygen that is of a clinically significant magnitude

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified