Predictors of clinically significant bleeding in patients with Dengue admitted to intensive care unit- Retrospective study
Not Applicable
- Conditions
- Health Condition 1: A91- Dengue hemorrhagic fever
- Registration Number
- CTRI/2022/10/046155
- Lead Sponsor
- DR PRIYA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Laboratory confirmed dengue patients
Primary Dengue: Positive NS1 antigen-based ELISA test or Immunoglobulin M (IgM) rapid test for dengue virus.
Secondary Dengue: IgG/IgM ratio � 1.1 (ELISA)
IgG cut off >3
Platelet count <100000 cells/ mm3
Exclusion Criteria
1.Co-infections with other pathogens
2.Patients with other causes of thrombocytopenia
ITP
Chronic liver disease
Haematological malignancies
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the Grades of Bleeding associated with thrombocytopenia. <br/ ><br>Severity of disease- Dengue Hemorrhagic Fever or Dengue Shock Syndrome. <br/ ><br>Duration of thrombocytopenia- Time to spontaneous recovery more than 50000 cells per cubic mm. <br/ ><br>Length of ICU stay <br/ ><br>Transfusion requirement <br/ ><br>Mortality <br/ ><br>Timepoint: 30 days
- Secondary Outcome Measures
Name Time Method Duration of thrombocytopenia <br/ ><br>Length of ICU stay <br/ ><br>Transfusion requirements <br/ ><br>mortalityTimepoint: 30 days