Magnesiumsulphate for Postoperative Analgesia In the Newly delivered, The MAG-PAIN randomized controlled trial.

Phase 2

Not yet recruiting

• Conditions: Postoperative pain
• Interventions: Drug: -

• Registration Number: 2024-519617-56-00
• Lead Sponsor: Region Halland

Brief Summary

The aim in this study is to investigate if adding intravenous magnesium-sulfate to pregnant women undergoing cesarean section can lead to improved postoperative pain outcomes.

Detailed Description

Not available

Study Timeline

• Study First Posted: 2025-03-17
• Last Update Posted: 2025-03-17

Recruitment & Eligibility

• Status: Authorised, recruitment pending
• Sex: Female
• Target Recruitment: 150

Inclusion Criteria

Adult over age 18. Cesarean section under spinal anesthesia. Participant should be able to accomodate information in Swedish

Exclusion Criteria

Cronic kidney desease stadium 3 or above. Not Swedish speaking. Contraindication towards spinal anesthesia. General anesthesia

Study & Design

• Study Type: Not specified
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
-	-	Participants receiving -

Primary Outcome Measures

Name	Time	Method
Acute postoperative pain within 6 hours		Acute postoperative pain within 6 hours

Secondary Outcome Measures

Name	Time	Method
Acute postoperative pain after 14 days, in both rest and movement.		Acute postoperative pain after 14 days, in both rest and movement.
Acute postoperative pain after 24 hours, in both rest and movement		Acute postoperative pain after 24 hours, in both rest and movement
Persistent postoperative pain after 3 months in both rest and movement.		Persistent postoperative pain after 3 months in both rest and movement.
Early recovery after 24 hours		Early recovery after 24 hours
Early recovery after 14 days.		Early recovery after 14 days.
Opioidconsumption. Total opioid dose in intravenous morphine milligram equivalents after 24 hours.		Opioidconsumption. Total opioid dose in intravenous morphine milligram equivalents after 24 hours.
Postoperative nausea and vomiting. Highest intensity after 24 hours.		Postoperative nausea and vomiting. Highest intensity after 24 hours.
Self-evaluated quality of breastfeeding and fetal connection. Highest score between 0 and 10 is compared between groups after 24 hours.		Self-evaluated quality of breastfeeding and fetal connection. Highest score between 0 and 10 is compared between groups after 24 hours.
Self-evaluated quality of breastfeeding and fetal connection. Highest score between 0 and 10 is compared between groups after 14 days.		Self-evaluated quality of breastfeeding and fetal connection. Highest score between 0 and 10 is compared between groups after 14 days.

Trial Locations

Locations (1)

Region Halland; 🇸🇪 Halmstad, Sweden

Region Halland

🇸🇪Halmstad, Sweden

Anna Persson

Site contact

0703047160

anna.p.persson@regionhalland.se