Evaluation of placenta by shear wave elastography
Not Applicable
- Conditions
- Health Condition 1: O09- Supervision of high risk pregnancy
- Registration Number
- CTRI/2024/05/067406
- Lead Sponsor
- All India Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Pregnant women diagnosed with a placental syndromes like fetal growth restriction, pre-eclampsia, diabetes mellitus (gestational and overt), spontaneous preterm delivery, premature rupture of membranes, placental abruption, or intrauterine fetal demise.
Exclusion Criteria
1.Iatrogenic preterm delivery
2.Cases with IUFD, are due to causes other than those, that can be attributed to placental abnormalities.
3.Posteriorly attached placenta
4.Patients with multiple pregnancy
5.Pregnancies with congenital anomalies in the fetus.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the accuracy, sensitivity, and specificity of Shear wave elastography, for assessing placental stiffness/fibrosis in patients with placental syndromes taking placental histopathology as the standard.Timepoint: Within one week of delivery and after delivery
- Secondary Outcome Measures
Name Time Method 3.To evaluate how placental stiffness as assessed by Shear wave elastography & placental fibrosis as assessed by histopathological examination, vary with maternal age, gravidity, parity, BMI, & area of interrogation within the placenta on stiffness measurements.Timepoint: At disease diagnosis, & within one week of delivery.;To find out whether changes in placental stiffness as assessed by Shear wave elastography correlate with disease severity in patients with placental syndromes.Timepoint: At disease diagnosis, & within one week of delivery.;To identify a threshold of placental stiffness, as measured by SWE, beyond which the chances of feto-maternal complications increase.Timepoint: SWE will be done twice, one at disease diagnosis, and second within one week of delivery.