Investigating the effectiveness of conditioned medium with IPL laser compared to extracellular vesicles with IPL laser in the treatment of rosacea

Phase 1

• Conditions: Rosacea.; Rosacea

• Registration Number: IRCT20200127046282N32
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 27 May 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Suffering from rosacea
Not receiving other treatments in the last three months
Eligible men and women from 18 to 60 years
with severe erythema rosacea based on a patient self-assessment (PSA) score of 4 (severe) and a physician evaluation of erythema (CEA) score of 3 or more
have the ability to enter the study

Exclusion Criteria

causing severe drug side effects
Those who had more than 5 inflammatory lesions on the face (pointy acne or purulent acne)
Specific forms of rosacea (rosacea conglobata, rosacea fulminans, isolated rhinophyma, isolated pastilosis of the chin)
They had other facial dermatitis similar to rosacea (such as perioral dermatitis), dimadisidosis, keratinization, seborrheic dermatitis, acute lupus erythematosus, or actinic telangiectasian.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of rosacea lesions based on physician assessment (CEA). Timepoint: Before treatment and 4 and 8 weeks after. Method of measurement: Physical examination.

Secondary Outcome Measures

Name	Time	Method
Severity of rosacea lesions based on patient self-assessment (PSA). Timepoint: Before treatment and 4 and 8 weeks after. Method of measurement: Questionnaire PSA (patient's self-assessment) (evaluating the severity of erythema and redness from the patient's perspective).